Proliferation- and cytotoxic immune signatures identify chemotherapy-responsive bladder tumors in a molecular subtype dependent manner

Abstract Neoadjuvant chemotherapy (NAC) followed by radical cystectomy (RC) has been the standard care for muscle-invasive bladder cancer (MIBC) for two decades. One third of NAC-treated patients achieve pathologic complete response (pT0N0), a proxy for improved survival after RC. Predicting respons...

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Bibliografische Detailangaben

Hauptverfasser:	Aymeric Zadoroznyj, Pontus Eriksson, Carina Bernardo, Lena Tran, Carl-Adam Mattsson, Thomas W. Flaig, Roland Seiler, Catherine M. Tangen, Peter C. Black, Seth P. Lerner, David J. McConkey, Mattias Höglund, Fredrik Liedberg, Gottfrid Sjödahl
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Portfolio 2026-07-01
Schriftenreihe:	npj Precision Oncology
Online-Zugang:	https://doi.org/10.1038/s41698-026-01588-7
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