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Exploring the Link between Nucleosome Occupancy and DNA Methylation

Near promoters, both nucleosomes and CpG sites form characteristic spatial patterns. Previously, nucleosome depleted regions were observed upstream of transcription start sites and nucleosome occupancy was reported to correlate both with CpG density and the level of CpG methylation. Several studies...

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Principais autores: Cecilia Lövkvist, Kim Sneppen, Jan O. Haerter
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2018-01-01
Serija:Frontiers in Genetics
Teme:
Online dostop:http://journal.frontiersin.org/article/10.3389/fgene.2017.00232/full
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