Subtracting the sequence bias from partially digested MNase-seq data reveals a general contribution of TFIIS to nucleosome positioning

Abstract Background TFIIS stimulates RNA cleavage by RNA polymerase II and promotes the resolution of backtracking events. TFIIS acts in the chromatin context, but its contribution to the chromatin landscape has not yet been investigated. Co-transcriptional chromatin alterations include subtle chang...

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Главные авторы:	Gabriel Gutiérrez, Gonzalo Millán-Zambrano, Daniel A. Medina, Antonio Jordán-Pla, José E. Pérez-Ortín, Xenia Peñate, Sebastián Chávez
Формат:	Artigo
Язык:	Inglês
Опубликовано:	BMC 2017-12-01
Серии:	Epigenetics & Chromatin
Предметы:	Nucleosome mapping MNase-seq MNase-sensitive nucleosomes TFIIS Nucleosomal fuzziness
Online-ссылка:	http://link.springer.com/article/10.1186/s13072-017-0165-x
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