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TXNIP deficiency attenuates renal fibrosis by modulating mTORC1/TFEB-mediated autophagy in diabetic kidney disease

Thioredoxin-interacting protein (TXNIP) is an important regulatory protein for thioredoxin (TRX) that elicits the generation of reactive oxygen species (ROS) by inhibiting the redox function of TRX. Abundant evidence suggests that TXNIP is involved in the fibrotic process of diabetic kidney disease...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Yunxia Du, Ming Wu, Shan Song, Yawei Bian, Yonghong Shi
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Taylor & Francis Group 2024-12-01
Rangatū:Renal Failure
Ngā marau:
Urunga tuihono:https://www.tandfonline.com/doi/10.1080/0886022X.2024.2338933
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