Meiotic DNA break resection and recombination rely on chromatin remodeler Fun30
Abstract DNA double-strand breaks (DSBs) are nucleolytically processed to generate single-stranded DNA for homologous recombination. In Saccharomyces cerevisiae meiosis, this resection involves nicking by the Mre11–Rad50–Xrs2 complex (MRX), then exonucleolytic digestion by Exo1. Chromatin remodeling...
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| Hlavní autoři: | , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Springer Nature
2024-11-01
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| Edice: | The EMBO Journal |
| Témata: | |
| On-line přístup: | https://doi.org/10.1038/s44318-024-00318-8 |
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