Enhancement of angiotensin II type 1 receptor-associated protein suppresses kidney inflammation in a mouse model of aristolochic acid nephropathy

Abstract Chronic kidney disease generally progresses to irreversible fibrosis through chronic inflammation and age-related changes. We had previously reported that genetic knockdown of angiotensin II type 1 receptor (AT1R)-associated protein (ATRAP) exacerbates aging-associated kidney tubulointersti...

Descripción completa

Detalles Bibliográficos

Autores principales:	Rika Furuta, Shingo Urate, Hiromichi Wakui, Tatsuki Uehara, Shunichiro Tsukamoto, Shinya Taguchi, Ryutaro Morita, Naohito Okami, Akio Yamashita, Kengo Azushima, Kouichi Tamura
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Nature Portfolio 2025-07-01
Colección:	Scientific Reports
Materias:	Angiotensin II type 1 receptor-associated protein Anti-aging genes Aristolochic acid nephropathy Chronic kidney disease Renal fibrosis
Acceso en línea:	https://doi.org/10.1038/s41598-025-08642-7
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!