Rapid In Vivo Validation of HDAC Inhibitor-Based Treatments in Neuroblastoma Zebrafish Xenografts

The survival rate among children with relapsed neuroblastomas continues to be poor, and thus new therapeutic approaches identified by reliable preclinical drug testing models are urgently needed. Zebrafish are a powerful vertebrate model in preclinical cancer research. Here, we describe a zebrafish...

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Detalhes bibliográficos

Principais autores:	Jagoda K Wrobel, Sara Najafi, Simay Ayhan, Charlotte Gatzweiler, Damir Krunic, Johannes Ridinger, Till Milde, Frank Westermann, Heike Peterziel, Benjamin Meder, Martin Distel, Olaf Witt, Ina Oehme
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2020-10-01
coleção:	Pharmaceuticals
Assuntos:	childhood cancer preclinical models precision medicine xenotransplantation small molecules histone deacetylases
Acesso em linha:	https://www.mdpi.com/1424-8247/13/11/345
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