Synergistic STING activation and oxidative cascades-induced ferroptosis drive tumor microenvironment remodeling by engineered manganese nanoreactors

In head and neck squamous cell carcinoma, a “cold” (immune-desert) tumor microenvironment promotes immunosuppression, which is a critical driver of disease recurrence and therapeutic resistance. To address this challenge, we develop an innovative strategy to remodel the tumor immune microenvironment...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Wa Li, Zihui Tang, Jiyang Xue
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Elsevier 2026-02-01
Цуврал:	Redox Biology
Нөхцлүүд:	Chemodynamical therapy Manganese nanoreactors Immunogenic cell death STING pathway Ferroptosis
Онлайн хандалт:	http://www.sciencedirect.com/science/article/pii/S2213231725004902
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!