Synergistic STING activation and oxidative cascades-induced ferroptosis drive tumor microenvironment remodeling by engineered manganese nanoreactors

In head and neck squamous cell carcinoma, a “cold” (immune-desert) tumor microenvironment promotes immunosuppression, which is a critical driver of disease recurrence and therapeutic resistance. To address this challenge, we develop an innovative strategy to remodel the tumor immune microenvironment...

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Λεπτομέρειες βιβλιογραφικής εγγραφής

Κύριοι συγγραφείς:	Wa Li, Zihui Tang, Jiyang Xue
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	Elsevier 2026-02-01
Σειρά:	Redox Biology
Θέματα:	Chemodynamical therapy Manganese nanoreactors Immunogenic cell death STING pathway Ferroptosis
Διαθέσιμο Online:	http://www.sciencedirect.com/science/article/pii/S2213231725004902
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