SIN3A promotes lung adenocarcinoma by repressing MIR22HG/Beclin1 axis-mediated autophagy and ferroptosis

Abstract Long noncoding RNAs (lncRNAs) are increasingly recognized as key regulators of lung adenocarcinoma (LUAD), yet for many lncRNAs the upstream repressors and downstream effector pathways remain unclear. Here, we identify MIR22HG as a frequently downregulated lncRNA in LUAD, and show that its...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Yongyang Chen, Miao Yin, Xiaobi Huang, Chang Liu, Yuexin Zheng, Honglian Zhou, Xiao Lei, Yuetong Jiang, Yanfeng Liang, Xiaoqing Xu, Quan Yang, Yudong Guo, Haiwen Li, Feiyu Long, Feiyu Niu, Zhixiong Yang, Wenmei Su
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2026-01-01
coleção:	European Journal of Medical Research
Assuntos:	MIR22HG Beclin1 SIN3A Autophagy Ferroptosis Lung adenocarcinoma
Acesso em linha:	https://doi.org/10.1186/s40001-026-03852-9
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!