SIN3A promotes lung adenocarcinoma by repressing MIR22HG/Beclin1 axis-mediated autophagy and ferroptosis

Abstract Long noncoding RNAs (lncRNAs) are increasingly recognized as key regulators of lung adenocarcinoma (LUAD), yet for many lncRNAs the upstream repressors and downstream effector pathways remain unclear. Here, we identify MIR22HG as a frequently downregulated lncRNA in LUAD, and show that its...

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Λεπτομέρειες βιβλιογραφικής εγγραφής

Κύριοι συγγραφείς:	Yongyang Chen, Miao Yin, Xiaobi Huang, Chang Liu, Yuexin Zheng, Honglian Zhou, Xiao Lei, Yuetong Jiang, Yanfeng Liang, Xiaoqing Xu, Quan Yang, Yudong Guo, Haiwen Li, Feiyu Long, Feiyu Niu, Zhixiong Yang, Wenmei Su
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	BMC 2026-01-01
Σειρά:	European Journal of Medical Research
Θέματα:	MIR22HG Beclin1 SIN3A Autophagy Ferroptosis Lung adenocarcinoma
Διαθέσιμο Online:	https://doi.org/10.1186/s40001-026-03852-9
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