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Activation of EphrinB2/EphB2 signaling in the spine cord alters glia-neuron interactions in mice with visceral hyperalgesia following maternal separation

BackgroundSress early in life has been linked to visceral hyperalgesia and associated functional gastrointestinal disorders. In a mouse model of visceral hyperalgesia, we investigated whether the EphB2 receptor and its EphrinB2 ligand in spinal cord contribute to dysregulation of glia-neuron interac...

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主要な著者: Shufen Guo, Yu Wang, Qingling Duan, Wei Gu, Qun Fu, Zhengliang Ma, Jiaping Ruan
フォーマット: Artigo
言語:Inglês
出版事項: Frontiers Media S.A. 2024-09-01
シリーズ:Frontiers in Pharmacology
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オンライン・アクセス:https://www.frontiersin.org/articles/10.3389/fphar.2024.1463339/full
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