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Impaired olfactory performance and anxiety-like behavior in a rat model of multiple sclerosis are associated with enhanced adenosine signaling in the olfactory bulb via A1R, A2BR, and A3R

The present study shows that animals with experimental autoimmune encephalomyelitis (EAE) exhibit olfactory dysfunction and impaired general cognitive abilities, as well as anxiety-like behavior. Olfactory dysfunction occurs on average at 2 dpi, well before the onset of the first motor signs of EAE...

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Principais autores: Andjela Stekic, Milorad Dragic, Jelena Stanojevic, Marina Zaric Kontic, Ivana Stevanovic, Milica Zeljkovic Jovanovic, Katarina Mihajlovic, Nadezda Nedeljkovic
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2024-07-01
Colecção:Frontiers in Cellular Neuroscience
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Acesso em linha:https://www.frontiersin.org/articles/10.3389/fncel.2024.1407975/full
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