Impaired olfactory performance and anxiety-like behavior in a rat model of multiple sclerosis are associated with enhanced adenosine signaling in the olfactory bulb via A1R, A2BR, and A3R

The present study shows that animals with experimental autoimmune encephalomyelitis (EAE) exhibit olfactory dysfunction and impaired general cognitive abilities, as well as anxiety-like behavior. Olfactory dysfunction occurs on average at 2 dpi, well before the onset of the first motor signs of EAE...

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Autors principals:	Andjela Stekic, Milorad Dragic, Jelena Stanojevic, Marina Zaric Kontic, Ivana Stevanovic, Milica Zeljkovic Jovanovic, Katarina Mihajlovic, Nadezda Nedeljkovic
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2024-07-01
Col·lecció:	Frontiers in Cellular Neuroscience
Matèries:	MS/EAE olfactory impairment adenosine signaling A1R A2BR A3R
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fncel.2024.1407975/full
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