TET2 mutation in acute myeloid leukemia: biology, clinical significance, and therapeutic insights
Abstract TET2 is a critical gene that regulates DNA methylation, encoding a dioxygenase protein that plays a vital role in the regulation of genomic methylation and other epigenetic modifications, as well as in hematopoiesis. Mutations in TET2 are present in 7%–28% of adult acute myeloid leukemia (A...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
BMC
2024-11-01
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| Σειρά: | Clinical Epigenetics |
| Θέματα: | |
| Διαθέσιμο Online: | https://doi.org/10.1186/s13148-024-01771-2 |
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