M6A demethylase ALKBH5 regulates FOXO1 mRNA stability and chemoresistance in triple-negative breast cancer

Resistance to chemotherapy is the main reason for treatment failure and poor prognosis in patients with triple-negative breast cancer (TNBC). Although the association of RNA N6-methyladenosine (m6A) modifications with therapy resistance is noticed, its role in the development of therapeutic resistan...

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Detalhes bibliográficos

Principais autores:	Xi Liu, Pan Li, Yuanfeng Huang, Hongsheng Li, Xin Liu, Yaxi Du, Xin Lin, Danyang Chen, Hao Liu, Yongchun Zhou
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2024-02-01
coleção:	Redox Biology
Assuntos:	Triple-negative breast cancer Chemoresistance ALKBH5 FOXO1 Reactive oxygen species
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2213231723003944
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