Metformin induces muscle atrophy by transcriptional regulation of myostatin via HDAC6 and FoxO3a
Abstract Background Skeletal muscle atrophy is a severe condition that involves loss of muscle mass and quality. Drug intake can also cause muscle atrophy. Biguanide metformin is the first‐line and most widely prescribed anti‐diabetic drug for patients with type 2 diabetes. The molecular mechanism o...
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| Autores principales: | , , , , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Wiley
2022-02-01
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| Colección: | Journal of Cachexia, Sarcopenia and Muscle |
| Materias: | |
| Acceso en línea: | https://doi.org/10.1002/jcsm.12833 |
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