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Dihydromyricetin ameliorates liver fibrosis via inhibition of hepatic stellate cells by inducing autophagy and natural killer cell-mediated killing effect

Abstract Background This study investigated the mechanisms underlying the preventive effect of dihydromyricetin (DHM) against liver fibrosis involving hepatic stellate cells (HSCs) and hepatic natural killer (NK) cells. Methods A carbon tetrachloride (CCl4)-induced liver fibrosis model was establish...

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Principais autores: Xi Zhou, Li Yu, Min Zhou, Pengfei Hou, Long Yi, Mantian Mi
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2021-06-01
Serier:Nutrition & Metabolism
Fag:
Dihydromyricetin
Natural killer cells
Hepatic stellate cells
Liver fibrosis
IFN-γ
Online adgang:https://doi.org/10.1186/s12986-021-00589-6
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