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Polypyridylruthenium(II) complexes exert anti-schistosome activity and inhibit parasite acetylcholinesterases.

Schistosomiasis affects over 200 million people and there are concerns whether the current chemotherapeutic control strategy (periodic mass drug administration with praziquantel (PZQ)-the only licenced anti-schistosome compound) is sustainable, necessitating the development of new drugs.We investiga...

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Библиографические подробности
Главные авторы: Madhu K Sundaraneedi, Bemnet A Tedla, Ramon M Eichenberger, Luke Becker, Darren Pickering, Michael J Smout, Siji Rajan, Phurpa Wangchuk, F Richard Keene, Alex Loukas, J Grant Collins, Mark S Pearson
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science (PLoS) 2017-12-01
Серии:PLoS Neglected Tropical Diseases
Online-ссылка:http://europepmc.org/articles/PMC5746282?pdf=render
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