Polypyridylruthenium(II) complexes exert anti-schistosome activity and inhibit parasite acetylcholinesterases.

Schistosomiasis affects over 200 million people and there are concerns whether the current chemotherapeutic control strategy (periodic mass drug administration with praziquantel (PZQ)-the only licenced anti-schistosome compound) is sustainable, necessitating the development of new drugs.We investiga...

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Autors principals:	Madhu K Sundaraneedi, Bemnet A Tedla, Ramon M Eichenberger, Luke Becker, Darren Pickering, Michael J Smout, Siji Rajan, Phurpa Wangchuk, F Richard Keene, Alex Loukas, J Grant Collins, Mark S Pearson
Format:	Artigo
Idioma:	Inglês
Publicat:	Public Library of Science (PLoS) 2017-12-01
Col·lecció:	PLoS Neglected Tropical Diseases
Accés en línia:	http://europepmc.org/articles/PMC5746282?pdf=render
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