Incidence and prognostic impact of U2AF1 mutations and other gene alterations in myelodysplastic neoplasms with isolated 20q deletion

Abstract Background In myelodysplastic neoplasms (MDS), the 20q deletion [del(20q)] is a recurrent chromosomal abnormality that it has a high co‐occurrence with U2AF1 mutations. Nevertheless, the prognostic impact of U2AF1 in these MDS patients is uncertain and the possible clinical and/or prognosti...

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Main Authors:	Martín I. Castillo, Villamón E. Ribate, Calabuig M. Muñoz, Sanz G. Santillana, Such E. Taboada, Mora E. Casterá, Calasanz M. J. Abinzano, Irigoyen A. Barranco, Collado R. Nieto, Vara M. Pampliega, M. L. Blanco, Álvarez S. deAndrés, Pérez J. deOteyza, Bernal T. delCastillo, Granada I. Font, Jerez A. Cayuela, M. Díez‐Campelo, Abellán R. Sánchez, Solano C. Vercet, Tormo M. Díaz, Grupo Español de Síndromes Mielodisplásicos (GESMD)
Format:	Artigo
Language:	Inglês
Published:	Wiley 2023-08-01
Series:	Cancer Medicine
Subjects:	20q deletion myelodysplastic neoplasms prognosis quantitative allele‐specific PCR U2AF1 mutations
Online Access:	https://doi.org/10.1002/cam4.6300
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