TAK1 is a pivotal therapeutic target for tumor progression and bone destruction in myeloma
Along with the tumor progression, the bone marrow microenvironment is skewed in multiple myeloma (MM), which underlies the unique pathophysiology of MM and confers aggressiveness and drug resistance in MM cells. TGF-β-activated kinase-1 (TAK1) mediates a wide range of intracellular signaling pathway...
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| Principais autores: | , , , , , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Ferrata Storti Foundation
2020-04-01
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| Colecção: | Haematologica |
| Acesso em linha: | https://haematologica.org/article/view/9713 |
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