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TAK1 is a pivotal therapeutic target for tumor progression and bone destruction in myeloma

Along with the tumor progression, the bone marrow microenvironment is skewed in multiple myeloma (MM), which underlies the unique pathophysiology of MM and confers aggressiveness and drug resistance in MM cells. TGF-β-activated kinase-1 (TAK1) mediates a wide range of intracellular signaling pathway...

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Автори: Jumpei Teramachi, Hirofumi Tenshin, Masahiro Hiasa, Asuka Oda, Ariunzaya Bat-Erdene, Takeshi Harada, Shingen Nakamura, Mohannad Ashtar, So Shimizu, Masami Iwasa, Kimiko Sogabe, Masahiro Oura, Shiro Fujii, Kumiko Kagawa, Hirokazu Miki, Itsuro Endo, Tatsuji Haneji, Toshio Matsumoto, Masahiro Abe
Формат: Artigo
Мова:Inglês
Опубліковано: Ferrata Storti Foundation 2020-04-01
Серія:Haematologica
Онлайн доступ:https://haematologica.org/article/view/9713
Теги: Додати тег
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