Mechanisms of glabridin inhibition of integrin αIIbβ3 inside-out signals and NF-κB activation in human platelets

Abstract Background Platelets play a crucial role in cardiovascular diseases (CVDs) and are activated by endogenous agonists like collagen. These agonists initiate signal transduction through specific platelet receptors, resulting in platelet aggregation. Glabridin, a prenylated isoflavonoid found i...

Celý popis

Podrobná bibliografie

Hlavní autoři:	Wei-Chieh Huang, Thanasekaran Jayakumar, Joen-Rong Sheu, Chih-Wei Hsia, Chih-Hsuan Hsia, Ting-Lin Yen, Chao-Chien Chang
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2023-06-01
Edice:	Chinese Medicine
Témata:	Glabridin Human platelets αIIbβ3 inside-out NF-κB Thromboembolic lungs Platelet plug formation
On-line přístup:	https://doi.org/10.1186/s13020-023-00779-9
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!