Caspase-Dependent Apoptosis Induced by Telomere Cleavage and TRF2 Loss

Chromosomal abnormalities involving telomeric associations (TAs) often precede replicative senescence and abnormal chromosome configurations. We report here that telomere cleavage following exposure to proapoptotic agents is an early event in apoptosis. Exposure of human and murine cancer cells to a...

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Xehetasun bibliografikoak
Egile Nagusiak:	Asha S. Multani, Mustafa Ozen, Satya Narayad, Virendra Kumar, Joya Chandra, David J. McConkey, Robert A. Newman, Sen Pathak
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Elsevier 2000-07-01
Saila:	Neoplasia: An International Journal for Oncology Research
Gaiak:	telomeric erosion DNA fragmentation caspase inhibitors fluorescence in situ hybridization telomeric-repeat binding factor (TRF)
Sarrera elektronikoa:	http://www.sciencedirect.com/science/article/pii/S1476558600800068
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Caspase-Dependent Apoptosis Induced by Telomere Cleavage and TRF2 Loss

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