Acacetin protects against depression-associated dry eye disease by regulating ubiquitination of NLRP3 through gp78 signal

Dry eye disease (DED) is a multifactorial syndrome that commonly occurs with depression. However, therapies targeting depression-related dry eye disease are rare. In the current study, we studied the beneficial effect of a natural flavone, acacetin, in depression-associated dry eye disease by utiliz...

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Detalhes bibliográficos

Principais autores:	Mingxia Xie, Hanqing Wang, Jun Peng, Dongqin Qing, Xi Zhang, Dongwei Guo, Pan Meng, Zhihong Luo, Xiaoye Wang, Qinghua Peng
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2022-10-01
coleção:	Frontiers in Pharmacology
Assuntos:	dry eye disease depression NLRP3 ubiquitination gp78 acacetin
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fphar.2022.984475/full
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