Identification of a broad sarbecovirus neutralizing antibody targeting a conserved epitope on the receptor-binding domain

Summary: Omicron, as the emerging variant with enhanced vaccine tolerance, has sharply disrupted most therapeutic antibodies. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) belongs to the subgenus Sarbecovirus, members of which share high sequence similarity. Herein, we report one sarb...

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Hlavní autoři:	Yanqun Wang, Zhaoyong Zhang, Minnan Yang, Xinyi Xiong, Qihong Yan, Lei Cao, Peilan Wei, Yuting Zhang, Lu Zhang, Kexin Lv, Jiantao Chen, Xuesong Liu, Xiaochu Zhao, Juxue Xiao, Shengnan Zhang, Airu Zhu, Mian Gan, Jingjun Zhang, Ruoxi Cai, Jianfen Zhuo, Yanjun Zhang, Haiyue Rao, Bin Qu, Yuanyuan Zhang, Lei Chen, Jun Dai, Linling Cheng, Qingtao Hu, Yaoqing Chen, Huibin Lv, Ray T.Y. So, Malik Peiris, Jingxian Zhao, Xiaoqing Liu, Chris Ka Pun Mok, Xiangxi Wang, Jincun Zhao
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2024-01-01
Edice:	Cell Reports
Témata:	CP: Immunology
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S2211124723016649
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