SARS-CoV-2 ferritin nanoparticle vaccines produce hyperimmune equine sera with broad sarbecovirus activity

Summary: The rapid emergence of SARS-CoV-2 variants of concern (VoC) and the threat of future zoonotic sarbecovirus spillover emphasizes the need for broadly protective next-generation vaccines and therapeutics. We utilized SARS-CoV-2 spike ferritin nanoparticle (SpFN), and SARS-CoV-2 receptor bindi...

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Autores principales:	Elizabeth J. Martinez, William C. Chang, Wei-Hung Chen, Agnes Hajduczki, Paul V. Thomas, Jaime L. Jensen, Misook Choe, Rajeshwer S. Sankhala, Caroline E. Peterson, Phyllis A. Rees, Jordan Kimner, Sandrine Soman, Caitlin Kuklis, Letzibeth Mendez-Rivera, Vincent Dussupt, Jocelyn King, Courtney Corbett, Sandra V. Mayer, Aldon Fernandes, Kripa Murzello, Tres Cookenham, Janine Hvizdos, Larry Kummer, Tricia Hart, Kathleen Lanzer, Julian Gambacurta, Matthew Reagan, Debbie Duso, Sandhya Vasan, Natalie D. Collins, Nelson L. Michael, Shelly J. Krebs, Gregory D. Gromowski, Kayvon Modjarrad, John Kaundinya, M. Gordon Joyce
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Elsevier 2024-10-01
Colección:	iScience
Materias:	Immunology Virology
Acceso en línea:	http://www.sciencedirect.com/science/article/pii/S2589004224018492
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