Pleiotropic expression quantitative trait loci are enriched in enhancers and transcription factor binding sites and impact more genes

Integrating expression quantitative trait loci (eQTL) data with genome-wide association studies (GWAS) enables the discovery of pleiotropic gene regulatory variants that influence a wide range of traits and disease susceptibilities. However, a comprehensive understanding of the distribution of pleio...

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Prif Awduron:	Aitor González, Pascale Paul
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	Elsevier 2024-12-01
Cyfres:	Computational and Structural Biotechnology Journal
Pynciau:	Genome-wide associations studies (GWAS), expression quantitative trait loci (eQTL) Pleiotropy Colocalization
Mynediad Ar-lein:	http://www.sciencedirect.com/science/article/pii/S200103702400391X
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