Shared genetic architecture between Alzheimer’s disease and psychiatric disorders revealed by multi-trait genome-wide analyses

Abstract Objective Clarify the shared genetic architecture between Alzheimer’s disease (AD) and major psychiatric disorders. Methods We integrated large GWAS summary datasets derived predominantly from individuals of European ancestry for AD and eight psychiatric disorders; estimated genome-wide gen...

وصف كامل

التفاصيل البيبلوغرافية

المؤلفون الرئيسيون:	Huajun Zhang, Liangzhuo Xie, Facai Meng, Jiangli Cui, Bo Ma, Yu Wang, Kai Zhang, Xingyu Miao
التنسيق:	Artigo
اللغة:	Inglês
منشور في:	BMC 2026-04-01
سلاسل:	BMC Medical Genomics
الموضوعات:	Alzheimer’s disease Psychiatric disorders Genetic correlation Colocalization analysis Expression quantitative trait loci (eQTL)
الوصول للمادة أونلاين:	https://doi.org/10.1186/s12920-026-02354-1
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!