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The impact of ERN1 endoribonuclease activity inhibition on TOB1, HBEGF, and TWIST1 genes expression in U87MG glioblastoma cells

Objective. It is known that inhibition of the endoplasmic reticulum transmembrane signaling protein (ERN1) suppresses the glioblastoma cells proliferation. The present study aims to investigate the impact of inhibition of ERN1 endoribonuclease and protein kinase activities on the TOB1, HBEGF, and TW...

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Tallennettuna:
Päätekijät: Minchenko Oleksandr H., Sliusar Myroslava Y., Viletska Yuliia M., Rudnytska Olha V., Kolybo Denys V.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Sciendo 2025-01-01
Sarja:Endocrine Regulations
Aiheet:
tob1
hbegf
twist1
gene expression
microrna
ern1 protein kinase
glioblastoma cells
Linkit:https://doi.org/10.2478/enr-2025-0004
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