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Single cell RNAseq signatures refined with combiroc enhance identification of NK cells in blood and solid tissues

Abstract Cytotoxic CD8 T lymphocytes (CTLs) and natural killer (NK) cells share the common objective of controlling infections and detecting and removing tumor cells, albeit through distinct target recognition mechanisms. Although CTLs belong to the adaptive immune system and NK cells are innate lym...

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Principais autores: Ivan Ferrari, Saveria Mazzara, Andrea Gobbini, Noemi Di Marzo, Mariacristina Crosti, Sergio Abrignani, Renata Grifantini, Mauro Bombaci, Riccardo L. Rossi
Format: Artigo
Sprog:Inglês
Udgivet: Nature Portfolio 2025-12-01
Serier:Scientific Reports
Fag:
scRNA-seq
Gene signatures
Biomarkers
R package
Combinatorics
Phenotype overlap
Online adgang:https://doi.org/10.1038/s41598-025-29876-5
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