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Single cell RNAseq signatures refined with combiroc enhance identification of NK cells in blood and solid tissues

Abstract Cytotoxic CD8 T lymphocytes (CTLs) and natural killer (NK) cells share the common objective of controlling infections and detecting and removing tumor cells, albeit through distinct target recognition mechanisms. Although CTLs belong to the adaptive immune system and NK cells are innate lym...

Deskribapen osoa

Gorde:
Egile Nagusiak: Ivan Ferrari, Saveria Mazzara, Andrea Gobbini, Noemi Di Marzo, Mariacristina Crosti, Sergio Abrignani, Renata Grifantini, Mauro Bombaci, Riccardo L. Rossi
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Portfolio 2025-12-01
Saila:Scientific Reports
Gaiak:
scRNA-seq
Gene signatures
Biomarkers
R package
Combinatorics
Phenotype overlap
Sarrera elektronikoa:https://doi.org/10.1038/s41598-025-29876-5
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