CT-derived brain volumes and plasma p-Tau217 for risk stratification of amyloid positivity in early-stage Alzheimer’s disease

Abstract Background Early detection of amyloid-β (Aβ) pathology is critical for timely intervention in Alzheimer’s disease (AD). While Aβ positron emission tomography (PET) and cerebrospinal fluid (CSF) biomarkers are accurate, their high cost and limited accessibility hinder routine use. We develop...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Sohyun Yim, Seongbeom Park, Kyoung Yoon Lim, Heekyoung Kang, Daeun Shin, Hyemin Jang, Michael Weiner, Henrik Zetterberg, Kaj Blennow, Fernando Gonzalez-Ortiz, Nicholas J. Ashton, Sung Hoon Kang, Jihwan Yun, Minyoung Chun, Eunjoo Kim, Heejin Kim, Duk L. Na, Jun Pyo Kim, Sang Won Seo, Kichang Kwak, K-ROAD study
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2025-10-01
coleção:	Alzheimer’s Research & Therapy
Assuntos:	Alzheimer’s disease Two-stage diagnostic workflow Amyloid status Computed tomography Plasma p-tau217 Machine learning
Acesso em linha:	https://doi.org/10.1186/s13195-025-01870-z
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!