Enhancing Tetrahydrocannabinol’s Therapeutic Efficacy in Inflammatory Bowel Disease: The Roles of Cannabidiol and the Cannabinoid 1 Receptor Allosteric Modulator ZCZ011

<b>Background/Objectives:</b> Current inflammatory bowel disease (IBD) treatments focus on symptomatic relief, highlighting the need for innovative approaches. Dysregulation of the cannabinoid 1 (CB1) receptor, part of the endocannabinoid system, is linked to colitis. While tetrahydrocannabinol (THC...

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Autori principali:	Dinesh Thapa, Mohan Patil, Leon N Warne, Rodrigo Carlessi, Marco Falasca
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2025-01-01
Serie:	Pharmaceuticals
Soggetti:	inflammatory bowel disease DSS-induced ulcerative colitis cannabinoid 1 receptor (CB1R) tetrahydrocannabinol (THC) CB1R allosteric modulator ZCZ011
Accesso online:	https://www.mdpi.com/1424-8247/18/2/148
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