क्यूआर कोड

FOS drives podocyte injury and renal fibrosis in diabetic kidney disease via direct Smad3 binding

Abstract Introduction Epithelial-mesenchymal transition (EMT) plays a crucial role in diabetic kidney disease (DKD), particularly in the context of podocyte EMT. However, the regulatory networks controlling EMT activation in podocytes remain incompletely mapped. The FOS proto-oncogene (FOS) has emer...

पूर्ण विवरण

में बचाया:
मुख्य लेखकों: Man Sun, Tianchi Yan, Wenjing Zhao, Zhifeng Cheng
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Springer 2026-04-01
श्रृंखला:Cellular and Molecular Life Sciences
विषय:
Diabetic kidney disease
FOS
EMT
Fibrosis
TGF-β/Smad3
ऑनलाइन पहुंच:https://doi.org/10.1007/s00018-026-06215-z
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