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HER2 gene assessment in liquid biopsy of gastric and esophagogastric junction cancer patients qualified for surgery

Abstract Background Amplification of HER2 gene (ERBB2) and overexpression of HER2 protein on cancer cells are found in 10–26% of gastric cancer (GC) and esophagogastric junction cancer (EGJC). Gene copy number variation (CNV) could be detected in these patients in liquid biopsy and in cancer cells....

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Hoofdauteurs: Anna Grenda, Kamila Wojas-Krawczyk, Tomasz Skoczylas, Paweł Krawczyk, Jadwiga Sierocińska-Sawa, Grzegorz Wallner, Janusz Milanowski
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BMC 2020-11-01
Reeks:BMC Gastroenterology
Onderwerpen:
Gastric cancer
Esophagogastric cancer
HER2 copy number
Liquid biopsy
Online toegang:http://link.springer.com/article/10.1186/s12876-020-01531-5
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