HER2 gene assessment in liquid biopsy of gastric and esophagogastric junction cancer patients qualified for surgery

Abstract Background Amplification of HER2 gene (ERBB2) and overexpression of HER2 protein on cancer cells are found in 10–26% of gastric cancer (GC) and esophagogastric junction cancer (EGJC). Gene copy number variation (CNV) could be detected in these patients in liquid biopsy and in cancer cells....

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Главные авторы:	Anna Grenda, Kamila Wojas-Krawczyk, Tomasz Skoczylas, Paweł Krawczyk, Jadwiga Sierocińska-Sawa, Grzegorz Wallner, Janusz Milanowski
Формат:	Artigo
Язык:	Inglês
Опубликовано:	BMC 2020-11-01
Серии:	BMC Gastroenterology
Предметы:	Gastric cancer Esophagogastric cancer HER2 copy number Liquid biopsy
Online-ссылка:	http://link.springer.com/article/10.1186/s12876-020-01531-5
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