Epac2 activation mediates glucagon‐induced glucogenesis in primary rat hepatocytes

ABSTRACT Aims/Introduction Glucagon plays an essential role in hepatic glucogenesis by enhancing glycogen breakdown, inducing gluconeogenesis, and suppressing glycogenesis. Moreover, glucagon increases cyclic adenosine monophosphate (cAMP) levels, thereby activating protein kinase A (PKA) and cAMP g...

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Bibliographic Details

Main Authors:	Yusuke Shiozaki‐Takagi, Nobuaki Ozaki, Yukiyasu Toyoda
Format:	Artigo
Language:	Inglês
Published:	Wiley 2024-04-01
Series:	Journal of Diabetes Investigation
Subjects:	EPAC Glucagon Glucogenic action
Online Access:	https://doi.org/10.1111/jdi.14142
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