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Standardization of Data Analysis for RT-QuIC-Based Detection of Chronic Wasting Disease

Chronic wasting disease (CWD) is a disease affecting cervids and is caused by prions accumulating as pathogenic fibrils in lymphoid tissue and the central nervous system. Approaches for detecting CWD prions historically relied on antibody-based assays. However, recent advancements in protein amplifi...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Gage R. Rowden, Catalina Picasso-Risso, Manci Li, Marc D. Schwabenlander, Tiffany M. Wolf, Peter A. Larsen
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2023-02-01
Schriftenreihe:Pathogens
Schlagworte:
RT-QuIC
real-time quaking-induced conversion
ELISA
diagnostics
chronic wasting disease
maxpoint ratio
Online-Zugang:https://www.mdpi.com/2076-0817/12/2/309
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