Long-term effectiveness and safety of methotrexate-tacrolimus combination therapy versus methotrexate monotherapy in reducing rheumatoid arthritis flares after TNF inhibitor discontinuation: a retrospective cohort study

Abstract Background This study evaluates the long-term effectiveness and safety of methotrexate-tacrolimus combination therapy compared to methotrexate monotherapy in maintaining successful tumor necrosis factor (TNF) inhibitor discontinuation in rheumatoid arthritis (RA) patients. Methods We retros...

Whakaahuatanga katoa

Ngā taipitopito rārangi puna kōrero

Ngā kaituhi matua:	Taio Naniwa, Mikiko Kajiura
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	BMC 2025-04-01
Rangatū:	BMC Rheumatology
Ngā marau:	Biological therapy Clinical remission Recurrence Rheumatoid arthritis Withdrawing treatment
Urunga tuihono:	https://doi.org/10.1186/s41927-025-00489-9
Ngā Tūtohu:	Tāpirihia he Tūtohu Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!