SMAD4 mutation drives gut microbiome shifts toward tumor progression in colorectal cancer

Abstract Background Colorectal cancer (CRC) progression is driven by a series of sequential mutations in key driver genes; however, the factors underlying tumor progression and metastasis remain poorly understood. Mutations in TP53 and SMAD4, in particular, are associated with CRC progression. Altho...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Travis J. Gates, Dechen Wangmo, Kyra M. Boorsma Bergerud, Bridget M. Keel, Christopher Staley, Subbaya Subramanian
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Springer 2025-10-01
Sarja:	Discover Oncology
Aiheet:	Gut microbiome SMAD4 Driver gene mutations Colorectal cancer Metastasis
Linkit:	https://doi.org/10.1007/s12672-025-02580-6
Tagit:	Lisää tagi Ei tageja, Lisää ensimmäinen tagi!