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Ubiquitin-specific protease 5 is required for the efficient repair of DNA double-strand breaks.

During the DNA damage response (DDR), ubiquitination plays an important role in the recruitment and regulation of repair proteins. However, little is known about elimination of the ubiquitination signal after repair is completed. Here we show that the ubiquitin-specific protease 5 (USP5), a deubiqui...

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Principais autores: Satoshi Nakajima, Li Lan, Leizhen Wei, Ching-Lung Hsieh, Vesna Rapić-Otrin, Akira Yasui, Arthur S Levine
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science (PLoS) 2014-01-01
סדרה:PLoS ONE
גישה מקוונת:http://europepmc.org/articles/PMC3891734?pdf=render
תגים: הוספת תג
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