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Ubiquitin-specific protease 5 is required for the efficient repair of DNA double-strand breaks.

During the DNA damage response (DDR), ubiquitination plays an important role in the recruitment and regulation of repair proteins. However, little is known about elimination of the ubiquitination signal after repair is completed. Here we show that the ubiquitin-specific protease 5 (USP5), a deubiqui...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Satoshi Nakajima, Li Lan, Leizhen Wei, Ching-Lung Hsieh, Vesna Rapić-Otrin, Akira Yasui, Arthur S Levine
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science (PLoS) 2014-01-01
Sarja:PLoS ONE
Linkit:http://europepmc.org/articles/PMC3891734?pdf=render
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