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Targeting Dynamical Binding Processes in the Design of Non-Antibiotic Anti-Adhesives by Molecular Simulation—The Example of FimH

Located at the tip of type I fimbria of Escherichia coli, the bacterial adhesin FimH is responsible for the attachment of the bacteria to the (human) host by specifically binding to highly-mannosylated glycoproteins located on the exterior of the host cell wall. Adhesion represents a necessary early...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Eva-Maria Krammer, Jerome de Ruyck, Goedele Roos, Julie Bouckaert, Marc F. Lensink
Hōputu: Artigo
Reo:Inglês
I whakaputaina: MDPI AG 2018-07-01
Rangatū:Molecules
Ngā marau:
Urunga tuihono:http://www.mdpi.com/1420-3049/23/7/1641
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