The agonistic TSPO ligand XBD173 attenuates the glial response thereby protecting inner retinal neurons in a murine model of retinal ischemia

Abstract Background Ligand-driven modulation of the mitochondrial translocator protein 18 kDa (TSPO) was recently described to dampen the neuroinflammatory response of microglia in a retinal light damage model resulting in protective effects on photoreceptors. We characterized the effects of the TSP...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Kristin Mages, Felix Grassmann, Herbert Jägle, Rainer Rupprecht, Bernhard H. F. Weber, Stefanie M. Hauck, Antje Grosche
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	BMC 2019-02-01
Sarja:	Journal of Neuroinflammation
Aiheet:	Retina TSPO Müller cell Microglia Gliosis Ischemia
Linkit:	http://link.springer.com/article/10.1186/s12974-019-1424-5
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