The agonistic TSPO ligand XBD173 attenuates the glial response thereby protecting inner retinal neurons in a murine model of retinal ischemia

Abstract Background Ligand-driven modulation of the mitochondrial translocator protein 18 kDa (TSPO) was recently described to dampen the neuroinflammatory response of microglia in a retinal light damage model resulting in protective effects on photoreceptors. We characterized the effects of the TSP...

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Xehetasun bibliografikoak

Egile Nagusiak:	Kristin Mages, Felix Grassmann, Herbert Jägle, Rainer Rupprecht, Bernhard H. F. Weber, Stefanie M. Hauck, Antje Grosche
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	BMC 2019-02-01
Saila:	Journal of Neuroinflammation
Gaiak:	Retina TSPO Müller cell Microglia Gliosis Ischemia
Sarrera elektronikoa:	http://link.springer.com/article/10.1186/s12974-019-1424-5
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