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ERK5 and cell proliferation: nuclear localization is what matters

ERK5, the last MAP kinase family member discovered, is activated by the upstream kinase MEK5 in response to growth factors and stress stimulation. MEK5-ERK5 pathway has been associated to different cellular processes, playing a crucial role in cell proliferation in normal and cancer cells by mechani...

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Autori principali: Nestor Gomez, Tatiana Erazo, Jose M Lizcano
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2016-09-01
Serie:Frontiers in Cell and Developmental Biology
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Accesso online:http://journal.frontiersin.org/Journal/10.3389/fcell.2016.00105/full
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