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Sea urchin embryo as a model organism for the rapid functional screening of tubulin modulators

Identification of antimitotic molecules that affect tubulin dynamics is a multistep procedure. It includes in vitro tubulin polymerization assay, studies of a cell cycle effect, and general cytotoxicity assessment. To simplify this lengthy screening protocol, we have introduced and validated an assa...

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Autors principals: Marina N. Semenova, Alexander Kiselyov, Victor V. Semenov
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis Group 2006-06-01
Col·lecció:BioTechniques
Accés en línia:https://www.future-science.com/doi/10.2144/000112193
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