Vesicular GABA transport expression in kisspeptin cells may contribute to the preovulatory gonadotropin surge

BackgroundThe neurotransmitter gamma-aminobutyric acid (GABA) plays a vital role in the modulation of reproductive function by controlling gonadotropin-releasing hormone (GnRH) secretion. Most kisspeptin neurons, which are key regulators of GnRH neurons, coexpress GABA and other neuropeptides. Howev...

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Bibliographic Details

Main Authors:	Henrique Rodrigues Vieira, Estela Guidini Ferrufino, Ligia M. M. de Sousa, Guilherme A Alves, Marina G. Martins, Jose Donato, Renata Frazao
Format:	Artigo
Language:	Inglês
Published:	Frontiers Media S.A. 2026-04-01
Series:	Frontiers in Endocrinology
Subjects:	cre-loxP system hypothalamic-pituitary-gonadal axis luteinizing hormone puberty Slc32a1
Online Access:	https://www.frontiersin.org/articles/10.3389/fendo.2026.1807596/full
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